Fig. 9A: Activation of C4 in the Lectin Pathway, Step 1

The binding of the MBL (or the ficolin) to various microbial carbohydrates activates the associated MASP2 giving it the enzymatic activity to split C4 into C4a and C4b. (Go to Fig. 9B)

Illustration of Activation of C4 in the Lectin Pathway, Step 1 .jpg by Gary E. Kaiser, Ph.D.
Professor of Microbiology, The Community College of Baltimore County, Catonsville Campus
This work is licensed under a Creative Commons Attribution 4.0 International License.
Based on a work at https://cwoer.ccbcmd.edu/science/microbiology/index_gos.html.

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Last updated: August, 2019
Please send comments and inquiries to Dr. Gary Kaiser